Increasing evidence suggests that low to moderate ethanol ingestion protects against the deleterious effects of subseque......

Background:Trigeminal neuralgia is a disorder of paroxysmal and severely disabling facial pain and continues to be a rea......

Objective: Large-conductance Ca2+-and voltage-activated K+(BKCa)channels are expressed in almost every tissue in central......

Purpose: Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland.Numerous studies have demonstra......

Objective: Physical inactivity and ageing are widely recognized as risk factors for the development of cardiovascular di......

Hypertension is a major risk factor for the development of strokes,coronary artery disease,heart failure,and renal disea......

Aim:Tanshinone Ⅱ-A sodium sulfonate (DS-201),a derivative of salvia miltiorrhiza,could activate BKCa channels and induc......

Neuropathic pain remains a significant clinical problem and is often resistant to conventional analgesics.Large conducta......

目的研究大电导钙激活钾通道(BKCa)激活剂异海松酸(ISO)对APP/PS1转基因阿尔茨海默病模型小鼠认知功能及突触可塑性的影响。方法应......

Large conductance Ca2+-activated K+ (BKCa) channel exhibits a phenotype-dependent expression on vascular smooth muscle c......

目的:研究自发性高血压大鼠(Spontaneously Hypertensive Rat,SHR)脑中动脉平滑肌细胞BKCa通道电生理特性和表达的变化。方法:应用......